Normally
with time, the cells in our body grow old and die and are replaced by new ones.
Sometimes, due to some abnormality or pathology, these cells do not die and the
whole process goes wrong. The new cells being produced and the old remaining
cells together form a mass that we call tumor.
According to
the American Brain Tumor Association, brain
tumors are the second leading cause of deaths due to cancers in children, the
second leading cause of deaths in males aged 20-39 and the fifth leading cause
among women aged 20-39. The estimated number of new cases that are expected to
be diagnosed in the US population in 2013 is 69,720.
A brain tumor can be primary or
secondary depending on the nature of origin or benign or malignant depending on
the nature of cell growth and morphology; benign tumors have a propensity to
stay in the brain, while a malignant tumor can spread to the surrounding areas.
Benign tumors occur more frequently in children and older adults. Malignant
brain tumors are more common in adults as compared to children.
Although the benign tumors can be
surgically removed and seldom grow back, however, unlike those elsewhere in the
body, the ones in the brain can cause serious problems and can also be life
threatening. A benign brain tumor can transform into malignant brain tumor
(also known as brain cancer). Malignant tumors are usually more problematic and
pose a more serious threat to life.
What causes
brain tumors? There is
still no satisfactory answer to this question. The possible factors that could
play a role in increasing the chances of a primary brain tumor are exposure to
radiation, inheritance, usage of cell phones was strongly debated upon but no
valid link could be found.
Symptoms of a brain tumor can
unfortunately be very challenging for the patients. They include seizures,
headaches, loss of motor and sensory functions, hearing loss, loss of vision,
deep venous thrombosis, fatigue, cognitive and behavioral changes, and
dysfunctional endocrine system. These symptoms depend on the nature, site, size
and severity of the tumor and might be made worse by surgery or other
procedures if complications occur.
Diagnosing a brain tumor is an intricate and
difficult journey. It is vital for the patients to understand the protocols and
the consequences of diagnostic procedures and methods. A thorough history and
neurological exam is the first step towards establishing a diagnosis followed by CT scan, MRI, x-ray, biopsy,
genetic profiling, laboratory tests that include lumbar puncture, myelogram evoked
potentials, audiometry, endocrine evaluation, perimetry, and a recently
developed technique called biomarker research.
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